Patents with Abstracts
Matrix made of polyester polymers entangled with hyaluronic polymers useful for supporting tissue repair
Seyedin and Spiro of ISTO Technologies, Missouri, developed matrix compositions to support the repair of tissue defects such as an osteochondral injury. A matrix consists of a polyester polymer entangled with a polysaccharide polymer. In certain configurations, a matrix can be a polyester cross-linked with a polysaccharide, which can be an oxidized polysaccharide. In some configurations, a matrix can further comprise one or more additional components, such as a growth factor. (RDC 6/19/2012)
Composition for promoting bone regeneration and restoration
|Kim et al of Hans Biomed, South Korea, developed a bone grafting material composite. The bone grafting material includes a demineralized bone matrix (DBM) and a carboxymethyl cellulose (CMC)/glycerol gel carrier. Due to the CMC/glycerol gel carrier, the implantation ability thereof is better than that of the DBM. Therefore, the bone grafting material composite can be easily used, so that a curative effect can be greatly improved. In addition, since the CMC/glycerol gel is used as a carrier, the composite with a mobility maintained is washed out by water after surgery, so that the composite can be fixed on a damaged portion of a bone. (RDC 6/19/2012)
PLGA/hydroxyapatite composite biomaterial by gas bubble formation
Kim of Nano Orthopedics, Florida, Tissue engineering developed a new composite bone graft material made from biocompatible poly(D,L-lactic-co-glycolic acid) (PLGA) and nano-sized hydroxyapatite particles exposed on its surface using a gas foaming particle leaching (GF/PL) method. A further embodiment of this invention involves coating this PLGA/hydroxyapatite biomaterial with an adherent, fast, uniform coating of a mineral such as apatite. The PLGA polymer portion of the composite provides sufficient mechanical strength to replace bone and is degradable over time to allow new bone tissue ingrowth. The incorporated hydroxyapatite particles increase the composite material's osteogenic properties by providing sites for tissue attachment and propagation. Finally, a uniform coating of mineral apatite on the surface of this novel biomaterial composite further enhances its osteogenic qualities. (RDC 5/24/2012)
Roger D. Corneliussen
Maro Polymer Links
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Copyright 2012 by Roger D. Corneliussen.
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** Date of latest addition; date of first entry is 5/24/2012.